biofilmsShah Adil Ishtiyaq Ahmad, S. M. Nayeemul Bari, Mohammad Mohiuddin

Department of Biotechnology and Genetic Engineering, Mawlana Bhashani Science and Technology University, Santosh, Tangail

Molecular Genetics Laboratory, International Center for Diarrheal Disease Research, Bangladesh (ICDDR,B), Mohakhali, Dhaka

Department of Biochemistry and Molecular Biology, University of Dhaka

Key words: Biofilm, EPS, mixed species biofilm.


Unicellular bacterium in nature prefers to gather round to form a surface attached multi-cellular consortium called biofilm rather than living as an isolated planktonic cell. Biofilms comprise of the bacterial cells attached to a biotic or abiotic surface and the extracellular polymeric substances excreted by the participant cells. Many bacteria can detect environmental signals and respond accordingly to form biofilm and to detach from it. Formation of biofilm is crucial for the survival of the bacteria in the environment and for their interaction within and out of the species.

Biofilm formation found inside the lumen of an indwelling cathetCells within biofilms are distinct from the free swimming planktonic cells – both physiologically and genetically. Such distinctive features are crucial for the maintenance of the biofilm structure. Biofilms provide the bacteria with various survival and metabolic advantages over the planktonic form. Mixed species biofilms better resemble the environmental biofilm consortia where a group of related bacteria gather onto a single surface and interact among them for the betterment of the whole community. This review discusses about the basic steps of biofilm formation and the specialties of this unique bacterial architecture.

Get the original articles in Source: Volume 2, Number 6, June 2012 – IJB

Published By: International Journal of Biosciences (IJB)

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